Presence of SNPs in GDF9 mRNA of Iranian Afshari Sheep
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Genetic Polymorphism of GDF9 Gene in Iranian Moghani Sheep Breed
The families of TGF-β proteins are the most important growth factors in the ovary for growth and differentiation of early ovarian follicles. Three related oocyte-derived members of the transforming growth factor-β superfamily namely growth differentiation factor 9 (GDF9), BMP15 and BMPR-IB have been shown to be essential for follicular growth and ovulation. Different mutations in the GDF9 gene ...
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Calpastatin is an endogenous inhibitor of calpain (calcium-dependent cysteine protease). Calpastatin activityis highly related to the rate of protein turnover and rate of meat tenderization. In order to characterize thestructure of calpastatin in Iranian Afshari breed of sheep, intron 6 and partial exon 7 of the L domain wereamplified and sequenced. A fragment of approximately...
متن کاملSimultaneous Presence of G1 and G4 Mutations in Growth Differentiation Factor 9 Gene of Iranian Sheep
The fecundity in sheep has been much interested for producers due to its economical importance. Growth differentiation factor 9 (GDF9) is an autosomal gene with over dominance effect for twosingle nucleotide polymorphisms(SNPs), which resulted in sterility in homozygote mutant ewes and additive effect for three SNPs, without showing sterility event. In the present study, DNA was extracted from ...
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عنوان ژورنال
دوره 5 شماره 4
صفحات 225- 230
تاریخ انتشار 2012-03-01
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